Beilstein J. Org. Chem.2020,16, 880–887, doi:10.3762/bjoc.16.79
microwave irradiations. Taking advantage of the propargyl alcohol moiety present on commercially available steroids, this classical strategy was applied to mestranol and lynestrenol, giving a collection of new complex 17-spirosteroids.
Keywords: diversity-orientedstrategy; 17-ethynyl-17-hydroxysteroids
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Graphical Abstract
Scheme 1:
Two diversity-oriented strategies: (a) Diversity installed during the construction of the skeleton;...